#Citalopram 20 mg anti anti stroke trial
No major adverse events were found in either group.Ĭitalopram is a safe and tolerable medication in patients with acute IS, which could improve the outcome in these patients.Īcute ischemic stroke citalopram functional outcome randomized clinical trial selective serotonin reuptake inhibitors stroke rehabilitation. There will probably remain in solution is 70, topoisomerase i cuts one of mixed nerves. 001), with risk ratio and number needed to treat of 2 (CI = 1.2-3) and 4 (CI = 2.5-8.6), respectively. Two vaccines are licensed now, although not subject to contamination of aseptic handling 8 tno study: Risk during aseptic handling. The primary outcome of the study was achieved in 57 patients (79%) in the citalopram and 39 patients (54%) in the placebo group ( P <. Of 144 eligible patients, 15 patients died (4 in the citalopram and 11 in the placebo group), and 21 patients did not complete the study follow-up period (10 in the citalopram and 11 in the placebo group).
#Citalopram 20 mg anti anti stroke registration
The primary outcome of the study was set to a 50% reduction in the 3-month National Institutes of Health Stroke Scale compared with the baseline scores (Clinical Trial Registration URL: Unique identifier: IRCT201203192150N2). Patients with depression were excluded throughout the study.
All patients received standard care, including physiotherapy. In one group, the patients received oral citalopram 20 mg (once daily), and in the other group, they received placebo. Thus, neurotransmitters can be thought of as the communication system of the brain. Neurotransmitters are manufactured and released by nerves and then travel and attach to nearby nerves. In a randomized, placebo-controlled clinical trial, 144 patients with acute IS were studied for 3 months. Citalopram is an antidepressant medication that affects neurotransmitters, the chemicals that nerves within the brain use to communicate with each other. If the patient was taking a high dose of the first agent, consider tapering to a lower dose before starting the new agent. In general, patients are started on a dose of between 10 to 20 mg once a day.
The aim of the present study was to evaluate the effectiveness of citalopram on 3-mounth outcome of nondepressed acute IS patients. Start new SSRI at a low dose (e.g., citalopram, escitalopram, or paroxetine10 mg/day sertraline 25 mg/day or fluoxetine 20 mg every-other-day). Citalopram tablets come in dosages of 20 milligrams (mg) and 40 mg the liquid form delivers 10 mg per 5 milliliters (mL). Ischemic stroke (IS) is one of the main causes of death and disability in the adult population, and recovery from it is a major health concern worldwide.
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